Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity

Direct in vivo administration of messenger RNA (mRNA) delivered in both naked and nanoparticle formats are actively investigated because the use of dendritic cells transfected ex vivo with mRNA for cancer therapy is expensive and needs significant infrastructure. Notably, intravenous and subcutaneou...

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Bibliographic Details
Main Authors: Phua, Kyle K. L., Staats, Herman F., Leong, Kam W., Nair, Smita K.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044635/
https://ncbi.nlm.nih.gov/pubmed/24894817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05128
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