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Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity

Direct in vivo administration of messenger RNA (mRNA) delivered in both naked and nanoparticle formats are actively investigated because the use of dendritic cells transfected ex vivo with mRNA for cancer therapy is expensive and needs significant infrastructure. Notably, intravenous and subcutaneou...

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Detalles Bibliográficos
Autores principales: Phua, Kyle K. L., Staats, Herman F., Leong, Kam W., Nair, Smita K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044635/
https://ncbi.nlm.nih.gov/pubmed/24894817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05128
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