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Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity
Direct in vivo administration of messenger RNA (mRNA) delivered in both naked and nanoparticle formats are actively investigated because the use of dendritic cells transfected ex vivo with mRNA for cancer therapy is expensive and needs significant infrastructure. Notably, intravenous and subcutaneou...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4044635/ https://ncbi.nlm.nih.gov/pubmed/24894817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05128 |
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