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The impact of age and CYP2C9 and VKORC1 variants on stable warfarin dose in the paediatric population

The influence of genetic variation on warfarin dose requirement is limited for paediatric patients. We performed a retrospective, cross-sectional study to examine the effect of variant CYP2C9 and VKORC1 genotypes on warfarin dose in 100 children. Those with VKORC1 genotype AA required 48% of the dos...

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Bibliografische gegevens
Hoofdauteurs: Vear, Susan I., Ayers, Gregory D., Van Driest, Sara L., Sidonio, Robert F., Stein, C. Michael, Ho, Richard H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043918/
https://ncbi.nlm.nih.gov/pubmed/24601977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12817
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