Validation of Clinical Testing for Warfarin Sensitivity: Comparison of CYP2C9-VKORC1 Genotyping Assays and Warfarin-Dosing Algorithms

Responses to warfarin (Coumadin) anticoagulation therapy are affected by genetic variability in both the CYP2C9 and VKORC1 genes. Validation of pharmacogenetic testing for warfarin responses includes demonstration of analytical validity of testing platforms and of the clinical validity of testing. W...

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Main Authors: Langley, Michael R., Booker, Jessica K., Evans, James P., McLeod, Howard L., Weck, Karen E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2009
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671339/
https://ncbi.nlm.nih.gov/pubmed/19324988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2009.080123
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