Ability of VKORC1 and CYP2C9 to Predict Therapeutic Warfarin Dose During the Initial Weeks of Therapy

BACKGROUND: CYP2C9 and VKORC1 genotypes predict therapeutic warfarin dose at initiation of therapy; however, the predictive ability of genetic information after a week or longer is unknown. Experts have hypothesized that genotype becomes irrelevant once International Normalized Ratio (INR) values ar...

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Auteurs principaux: Ferder, Nicholas, Eby, Charles S., Deych, Elena, Harris, Jenine K., Ridker, Paul M., Milligan, Paul, Goldhaber, Samuel Z., King, Cristi R., Giri, Tusar, McLeod, Howard L., Glynn, Robert J., Gage, Brian F.
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718044/
https://ncbi.nlm.nih.gov/pubmed/19874474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2009.03677.x
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