Warfarin dose and INR related to genotypes of CYP2C9 and VKORC1 in patients with myocardial infarction

BACKGROUND: Warfarin treatment has a narrow therapeutic range, requiring meticulous monitoring and dosage titration. Individual dosage requirement has recently partly been explained by genetic variation of the warfarin metabolizing enzyme CYP2C9 and the Vitamin K-activating enzyme VKORC1. In the WAR...

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Bibliografiske detaljer
Main Authors: Haug, Kari Bente Foss, Sharikabad, Mohammad N, Kringen, Marianne K, Narum, Sigrid, Sjaatil, Stine T, Johansen, Per Wiik, Kierulf, Peter, Seljeflot, Ingebjørg, Arnesen, Harald, Brørs, Odd
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Original Clinical Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440373/
https://ncbi.nlm.nih.gov/pubmed/18559094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-9560-6-7
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