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The impact of age and CYP2C9 and VKORC1 variants on stable warfarin dose in the paediatric population
The influence of genetic variation on warfarin dose requirement is limited for paediatric patients. We performed a retrospective, cross-sectional study to examine the effect of variant CYP2C9 and VKORC1 genotypes on warfarin dose in 100 children. Those with VKORC1 genotype AA required 48% of the dos...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4043918/ https://ncbi.nlm.nih.gov/pubmed/24601977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12817 |
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