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14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)
p27(Kip1) (p27), a CDK inhibitor, migrates into the nucleus, where it controls cyclin–CDK complex activity for proper cell cycle progression. We report here that the classical bipartite-type basic amino-acid cluster and the two downstream amino acids of the C-terminal region of p27 function as a nuc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC404318/ https://ncbi.nlm.nih.gov/pubmed/15057270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600198 |
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