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14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)

p27(Kip1) (p27), a CDK inhibitor, migrates into the nucleus, where it controls cyclin–CDK complex activity for proper cell cycle progression. We report here that the classical bipartite-type basic amino-acid cluster and the two downstream amino acids of the C-terminal region of p27 function as a nuc...

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Autors principals: Sekimoto, Toshihiro, Fukumoto, Masahiro, Yoneda, Yoshihiro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC404318/
https://ncbi.nlm.nih.gov/pubmed/15057270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600198
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