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Importin α Protein Acts as a Negative Regulator for Snail Protein Nuclear Import

Snail, a zinc finger-containing transcriptional regulator, migrates into the nucleus where it controls gene expression. We demonstrated previously that importin β1 directly recognizes the zinc finger domain of Snail and transports it into the nucleus. Here, using in vitro and in vivo assays, we show...

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Detalhes bibliográficos
Main Authors: Sekimoto, Toshihiro, Miyamoto, Yoshimi, Arai, Shouko, Yoneda, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083189/
https://ncbi.nlm.nih.gov/pubmed/21454664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.213579
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