Importin α Protein Acts as a Negative Regulator for Snail Protein Nuclear Import

Snail, a zinc finger-containing transcriptional regulator, migrates into the nucleus where it controls gene expression. We demonstrated previously that importin β1 directly recognizes the zinc finger domain of Snail and transports it into the nucleus. Here, using in vitro and in vivo assays, we show...

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Bibliografiske detaljer
Main Authors: Sekimoto, Toshihiro, Miyamoto, Yoshimi, Arai, Shouko, Yoneda, Yoshihiro
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083189/
https://ncbi.nlm.nih.gov/pubmed/21454664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.213579
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