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CpG Oligodeoxynucleotides Enhance the Activities of CD8+ Cytotoxic T-Lymphocytes Generated by Combined hMUC1 Vaccination and hNIS Radioiodine Gene Therapy

PURPOSE: The authors evaluated whether the cytotoxicity of CD8+CTLs generated by combined hMUC1 vaccination and hNIS radioiodine gene therapy was enhanced in the presence of CpG in an established tumor model. METHODS: CMNF cells (CT26 cells expressing hMUC1, hNIS and Firefly luciferase) were transpl...

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Main Authors: Jeon, Yong Hyun, Choi, Yun, Lee, Jaetae, Kim, Chul Woo, Chung, June-Key
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042931/
https://ncbi.nlm.nih.gov/pubmed/24899950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13139-010-0039-7
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