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The combination of ANT2 shRNA and hNIS radioiodine gene therapy increases CTL cytotoxic activity through the phenotypic modulation of cancer cells: combination treatment with ANT2 shRNA and I-131

BACKGROUND: It is important to simultaneously induce strong cell death and antitumor immunity in cancer patients for successful cancer treatment. Here, we investigated the cytotoxic and phenotypic modulation effects of the combination of ANT2 shRNA and human sodium iodide symporter (hNIS) radioiodin...

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Detalhes bibliográficos
Main Authors: Choi, Yun, Lee, Ho Won, Lee, Jaetae, Jeon, Yong Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653759/
https://ncbi.nlm.nih.gov/pubmed/23522027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-143
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