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ANT2 suppression by shRNA restores miR-636 expression, thereby downregulating Ras and inhibiting tumorigenesis of hepatocellular carcinoma

MicroRNAs (miRNAs) participate in diverse biological functions and carcinogenesis by inhibiting specific gene expression. We previously reported that suppression of adenine nucleotide translocase 2 (ANT2) by using the short hairpin RNA (shRNA) approach has an antitumor effect in several cancer cells...

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Detalhes bibliográficos
Main Authors: Jang, Ji-Young, Lee, Young-Sin, Jeon, Yoon-Kyung, Lee, Kyoungbun, Jang, Ja-June, Kim, Chul-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584659/
https://ncbi.nlm.nih.gov/pubmed/23306701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.1
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