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Structural and kinetic determinants of protease substrates

The structural repertoire and kinetic threshold distinguishing legitimate signaling substrates are fundamental questions in proteolytic networks and pathways. We used N-terminal proteomics to address these issues by identifying cleavage-sites within the Escherichia coli proteome driven by the apopto...

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Bibliografske podrobnosti
Main Authors: Timmer, John C., Zhu, Wenhong, Pop, Cristina, Regan, Tim, Snipas, Scott J., Eroshkin, Alexey M., Riedl, Stefan J., Salvesen, Guy S.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042863/
https://ncbi.nlm.nih.gov/pubmed/19767749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1668
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