Characterization of HPV DNA methylation of contiguous CpG sites by bisulfite treatment and massively parallel sequencing—the FRAGMENT approach

Invasive cervix cancer (ICC) is the third most common malignant tumor in women and human papillomavirus 16 (HPV16) causes more than 50% of ICC. DNA methylation is a covalent modification predominantly occurring at CpG dinucleotides and increased methylation across the HPV16 genome is strongly associ...

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Main Authors: Sun, Chang, McAndrew, Thomas, Smith, Benjamin C., Chen, Zigui, Frimer, Marina, Burk, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2014
Assuntos:
Genetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042685/
https://ncbi.nlm.nih.gov/pubmed/24917876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00150
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