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Methylation of HPV16 genome CpG sites is associated with cervix precancer and cancer

OBJECTIVE: Invasive cervix cancer (ICC) is the second most common malignant tumor in women. Human papillomavirus 16 (HPV16) causes more than 50% of all ICC and is a major cause of cervix intraepithelial neoplasia (CIN). DNA methylation is a covalent modification predominantly occurring at CpG dinucl...

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Detalhes bibliográficos
Main Authors: Sun, Chang, Reimers, Laura L., Burk, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062667/
https://ncbi.nlm.nih.gov/pubmed/21306759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2011.01.013
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