HPV16 CpG methyl-haplotypes are associated with cervix precancer and cancer in the Guanacaste natural history study

OBJECTIVE: To evaluate HPV16 CpG methylation and methyl-haplotypes and their association with cervix precancer and cancer utilizing massively parallel single molecule next-generation sequencing (NGS). METHODS: A nested case-control study of HPV16 positive women was performed in a prospective cohort...

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Veröffentlicht in:Gynecol Oncol
Hauptverfasser: Frimer, Marina, Sun, Chang, McAndrew, Thomas, Smith, Benjamin, Harari, Ariana, Chen, Zigui, Mirabello, Lisa, Wentzensen, Nicolas, Goldberg, Gary L., Rodriguez, Ana C., Schiffman, Mark, Burk, Robert D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867226/
https://ncbi.nlm.nih.gov/pubmed/26001326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2015.05.001
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