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Non-random distribution of methyl-CpG sites and non-CpG methylation in the human rDNA promoter identified by next generation bisulfite sequencing

A next generation bisulfite sequencing (NGBS) was used to study rDNA promoter methylation in human brain using postmortem samples of the parietal cortex. Qualitative analysis of patterns of CpG methylation was performed at the individual rDNA unit level. CpG site-specific differences in methylation...

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Detalhes bibliográficos
Publicado no:Gene
Main Authors: Pietrzak, Maciej, Rempala, Grzegorz A., Nelson, Peter T., Hetman, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934664/
https://ncbi.nlm.nih.gov/pubmed/27008990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2016.03.028
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