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Non-random distribution of methyl-CpG sites and non-CpG methylation in the human rDNA promoter identified by next generation bisulfite sequencing

A next generation bisulfite sequencing (NGBS) was used to study rDNA promoter methylation in human brain using postmortem samples of the parietal cortex. Qualitative analysis of patterns of CpG methylation was performed at the individual rDNA unit level. CpG site-specific differences in methylation...

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Bibliografske podrobnosti
izdano v:Gene
Main Authors: Pietrzak, Maciej, Rempala, Grzegorz A., Nelson, Peter T., Hetman, Michal
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934664/
https://ncbi.nlm.nih.gov/pubmed/27008990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2016.03.028
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