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Non-random distribution of methyl-CpG sites and non-CpG methylation in the human rDNA promoter identified by next generation bisulfite sequencing

A next generation bisulfite sequencing (NGBS) was used to study rDNA promoter methylation in human brain using postmortem samples of the parietal cortex. Qualitative analysis of patterns of CpG methylation was performed at the individual rDNA unit level. CpG site-specific differences in methylation...

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Publicado en:Gene
Main Authors: Pietrzak, Maciej, Rempala, Grzegorz A., Nelson, Peter T., Hetman, Michal
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934664/
https://ncbi.nlm.nih.gov/pubmed/27008990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2016.03.028
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