Caricamento...
Transcriptional stalling in B-lymphocytes: A mechanism for antibody diversification and maintenance of genomic integrity
B cells utilize three DNA alteration strategies—V(D)J recombination, somatic hypermutation (SHM) and class switch recombination (CSR)—to somatically mutate their genome, thereby expressing a plethora of antibodies tailor-made against the innumerable antigens they encounter while in circulation. Of t...
Salvato in:
| Autori principali: | , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4042586/ https://ncbi.nlm.nih.gov/pubmed/23584095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.24556 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|