Enhanced somatic mutation rates induced in stem cells of mice by low chronic exposure to ethylnitrosourea.

We have found that the somatic mutation rate at the Dlb-1 locus increases exponentially during low daily exposure to ethylnitrosourea over 4 months. This effect, enhanced mutagenesis, was not observed at a lacI transgene in the same tissue, although the two loci respond very similarly to acute doses...

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Detaylı Bibliyografya
Asıl Yazarlar: Shaver-Walker, P M, Urlando, C, Tao, K S, Zhang, X B, Heddle, J A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC40423/
https://ncbi.nlm.nih.gov/pubmed/8524785
Etiketler: Etiketle
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