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Inferring Somatic Mutation Rates Using the Stop-Enhanced Green Fluorescent Protein Mouse
A new method is developed for estimating rates of somatic mutation in vivo. The stop-enhanced green fluorescent protein (EGFP) transgenic mouse carries multiple copies of an EGFP gene with a premature stop codon. The gene can revert to a functional form via point mutations. Mice treated with a poten...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright © 2007 by the Genetics Society of America
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2013726/ https://ncbi.nlm.nih.gov/pubmed/17603123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.069310 |
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