Stilbene Induced Inhibition of Androgen Receptor Dimerization: Implications for AR and ARΔLBD-Signalling in Human Prostate Cancer Cells

BACKGROUND: Advanced castration resistant prostate cancer (CRPC) is often characterized by an increase of C-terminally truncated, constitutively active androgen receptor (AR) variants. Due to the absence of a ligand binding domain located in the AR-C-terminus, these receptor variants (also termed AR...

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Main Authors: Streicher, Wolfgang, Luedeke, Manuel, Azoitei, Anca, Zengerling, Friedemann, Herweg, Alexander, Genze, Felicitas, Schrader, Mark G., Schrader, Andres J., Cronauer, Marcus V.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041728/
https://ncbi.nlm.nih.gov/pubmed/24887556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098566
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