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Effects of Sorafenib on C-Terminally Truncated Androgen Receptor Variants in Human Prostate Cancer Cells

Recent evidence suggests that the development of castration resistant prostate cancer (CRPCa) is commonly associated with an aberrant, ligand-independent activation of the androgen receptor (AR). A putative mechanism allowing prostate cancer (PCa) cells to grow under low levels of androgens, is the...

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Detalhes bibliográficos
Main Authors: Zengerling, Friedemann, Streicher, Wolfgang, Schrader, Andres J., Schrader, Mark, Nitzsche, Bianca, Cronauer, Marcus V., Höpfner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472761/
https://ncbi.nlm.nih.gov/pubmed/23109869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms130911530
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