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Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy

Despite 30 years of effort, there is no effective vaccine for HIV-1. However, antibodies can prevent HIV-1 infection in humanized mice and macaques when passively transferred. New single-cell-based methods have uncovered many broad and potent donor-derived antibodies, and structural studies have rev...

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Hlavní autoři: West, Anthony P., Scharf, Louise, Scheid, Johannes F., Klein, Florian, Bjorkman, Pamela J., Nussenzweig, Michel C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041625/
https://ncbi.nlm.nih.gov/pubmed/24529371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.01.052
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