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5-Fluorouracil affects assembly of stress granules based on RNA incorporation
The antimetabolite 5-fluorouracil is a widely used chemotherapeutic for the treatment of several solid cancers. However, resistance to 5-fluorouracil remains a major drawback in its clinical use. In this study we report that treatment of HeLa cells with 5-fluorouracil resulted in de novo assembly of...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4041438/ https://ncbi.nlm.nih.gov/pubmed/24728989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku264 |
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