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FOX-2 Dependent Splicing of Ataxin-2 Transcript Is Affected by Ataxin-1 Overexpression

Alternative splicing is a fundamental posttranscriptional mechanism for controlling gene expression, and splicing defects have been linked to various human disorders. The splicing factor FOX-2 is part of a main protein interaction hub in a network related to human inherited ataxias, however, its imp...

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Detalhes bibliográficos
Main Authors: Welzel, Franziska, Kaehler, Christian, Isau, Melanie, Hallen, Linda, Lehrach, Hans, Krobitsch, Sylvia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364202/
https://ncbi.nlm.nih.gov/pubmed/22666429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037985
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