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Ataxin-2 Interacts with the DEAD/H-Box RNA Helicase DDX6 and Interferes with P-Bodies and Stress Granules

Tight control of translation is fundamental for eukaryotic cells, and deregulation of proteins implicated contributes to numerous human diseases. The neurodegenerative disorder spinocerebellar ataxia type 2 is caused by a trinucleotide expansion in the SCA2 gene encoding a lengthened polyglutamine s...

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Bibliografiska uppgifter
Huvudupphovsmän: Nonhoff, Ute, Ralser, Markus, Welzel, Franziska, Piccini, Ilaria, Balzereit, Daniela, Yaspo, Marie-Laure, Lehrach, Hans, Krobitsch, Sylvia
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838996/
https://ncbi.nlm.nih.gov/pubmed/17392519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-12-1120
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