Siglec-G–CD24 axis controls the severity of graft-versus-host disease in mice

Activation of sialic-acid–binding immunoglobulin-like lectin-G (Siglec-G) by noninfectious damage-associated molecular patterns controls innate immune responses. However, whether it also regulates T-cell–mediated adaptive immune responses is not known. Graft-versus-host reaction is a robust adaptive...

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Bibliographic Details
Main Authors: Toubai, Tomomi, Hou, Guoqing, Mathewson, Nathan, Liu, Chen, Wang, Ying, Oravecz-Wilson, Katherine, Cummings, Emily, Rossi, Corinne, Evers, Rebecca, Sun, Yaping, Wu, Julia, Choi, Sung Won, Fang, Dexing, Zheng, Pan, Liu, Yang, Reddy, Pavan
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2014
Subjects:
Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041170/
https://ncbi.nlm.nih.gov/pubmed/24695850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-12-545335
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