Ikaros deficiency in host hematopoietic cells separates GVL from GVHD after experimental allogeneic hematopoietic cell transplantation

The graft-versus-leukemia (GVL) effect following allogeneic hematopoietic stem cell transplantation (allo-HCT) is critical for its curative potential. Hwever, GVL is tightly linked to graft-versus-host disease (GVHD). Among hematological malignancies, acute lymphoblastic leukemia (ALL) is the most r...

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Publicat a:Oncoimmunology
Autors principals: Toubai, Tomomi, Guoqing, Hou, Rossi, Corrine, Mathewson, Nathan, Oravecz-Wilson, Katherine, Cummings, Emily, Wu, Julia, Sun, Yaping, Choi, Sung, Reddy, Pavan
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485841/
https://ncbi.nlm.nih.gov/pubmed/26140241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1016699
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