Fos expression in response to dopamine D3-preferring phenylpiperazine drugs given with and without cocaine

WC 44 and WC 10 are phenylpiperazines with low (23 fold) to moderate (42 fold) selectivity for dopamine D3 receptors (D3Rs) over D2Rs, respectively. WC 44 is a full D3R agonist in the forskolin-stimulated adenylyl cyclase (AC) assay, whereas WC 10 has little efficacy. In contrast to their opposite e...

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Detalhes bibliográficos
Main Authors: Nolan, Brian C., Liu, Shinban, Hammerslag, Lindsey R., Cheung, Timothy H. C., Lenz, Jeffrey, Mach, Robert H., Luedtke, Robert R., Neisewander, Janet L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041163/
https://ncbi.nlm.nih.gov/pubmed/23766142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21691
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