Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells

Mitochondrial respiratory chain disorders are characterized by loss of electron transport chain (ETC) activity. Although the causes for many such diseases are known, there is a lack of effective therapies. To identify genes that confer resistance to severe ETC dysfunction when inactivated, we perfor...

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Bibliografiset tiedot
Päätekijät: Chen, Walter W, Birsoy, Kivanc, Mihaylova, Maria M, Snitkin, Harriet, Stasinski, Iwona, Yucel, Burcu, Bayraktar, Erol C, Carette, Jan E, Clish, Clary B, Brummelkamp, Thijn R, Sabatini, David D, Sabatini, David M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040975/
https://ncbi.nlm.nih.gov/pubmed/24685140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.046
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