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Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells

Mitochondrial respiratory chain disorders are characterized by loss of electron transport chain (ETC) activity. Although the causes for many such diseases are known, there is a lack of effective therapies. To identify genes that confer resistance to severe ETC dysfunction when inactivated, we perfor...

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Bibliografske podrobnosti
Main Authors: Chen, Walter W, Birsoy, Kivanc, Mihaylova, Maria M, Snitkin, Harriet, Stasinski, Iwona, Yucel, Burcu, Bayraktar, Erol C, Carette, Jan E, Clish, Clary B, Brummelkamp, Thijn R, Sabatini, David D, Sabatini, David M
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040975/
https://ncbi.nlm.nih.gov/pubmed/24685140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.046
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