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The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells

Identification of new molecular targets for the treatment of breast cancer is an important clinical goal, especially for triple-negative breast cancer, which is refractory to existing targeted treatments. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor known primarily...

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Autores principales: O'Donnell, E F, Koch, D C, Bisson, W H, Jang, H S, Kolluri, S K
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040680/
https://ncbi.nlm.nih.gov/pubmed/24481452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.549
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