The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor

BACKGROUND: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The AhR influences a variety of processes involved in cellular growth and differentiation, and recent studies have suggested...

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Detalhes bibliográficos
Main Authors: O'Donnell, Edmond F., Saili, Katerine S., Koch, Daniel C., Kopparapu, Prasad R., Farrer, David, Bisson, William H., Mathew, Lijoy K., Sengupta, Sumitra, Kerkvliet, Nancy I., Tanguay, Robert L., Kolluri, Siva Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948512/
https://ncbi.nlm.nih.gov/pubmed/20957046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013128
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