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The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor

BACKGROUND: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The AhR influences a variety of processes involved in cellular growth and differentiation, and recent studies have suggested...

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Detaylı Bibliyografya
Asıl Yazarlar: O'Donnell, Edmond F., Saili, Katerine S., Koch, Daniel C., Kopparapu, Prasad R., Farrer, David, Bisson, William H., Mathew, Lijoy K., Sengupta, Sumitra, Kerkvliet, Nancy I., Tanguay, Robert L., Kolluri, Siva Kumar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948512/
https://ncbi.nlm.nih.gov/pubmed/20957046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013128
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