The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor

BACKGROUND: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The AhR influences a variety of processes involved in cellular growth and differentiation, and recent studies have suggested...

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Bibliografische gegevens
Hoofdauteurs: O'Donnell, Edmond F., Saili, Katerine S., Koch, Daniel C., Kopparapu, Prasad R., Farrer, David, Bisson, William H., Mathew, Lijoy K., Sengupta, Sumitra, Kerkvliet, Nancy I., Tanguay, Robert L., Kolluri, Siva Kumar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948512/
https://ncbi.nlm.nih.gov/pubmed/20957046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013128
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