The aryl hydrocarbon receptor is required for induction of p21(cip1/waf1) expression and growth inhibition by SU5416 in hepatoma cells

The aryl hydrocarbon receptor (AhR) is a potential clinical target for cancer and autoimmune dysfunction. Identifying selective AhR modulators that produce desirable clinical outcomes represents an opportunity for developing new anti-cancer agents. Repurposing clinically-used drugs with established...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: O’Donnell, Edmond F., Jang, Hyo Sang, Pearce, Martin, Kerkvliet, Nancy I, Kolluri, Siva Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421923/
https://ncbi.nlm.nih.gov/pubmed/28424418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16056
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