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Single-molecule assay reveals strand switching and enhanced processivity of UvrD
DNA helicases are enzymes capable of unwinding double-stranded DNA (dsDNA) to provide the single-stranded DNA template required in many biological processes. Among these, UvrD, an essential DNA repair enzyme, has been shown to unwind dsDNA while moving 3′-5′ on one strand. Here, we use a single-mole...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC404063/ https://ncbi.nlm.nih.gov/pubmed/15079074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306713101 |
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