Direct imaging of single UvrD helicase dynamics on long single-stranded DNA

Fluorescence imaging of single-protein dynamics on DNA has been largely limited to double-stranded DNA or short single-stranded DNA. We have developed a hybrid approach for observing single proteins moving on laterally stretched kilobase-sized ssDNA. Here we probed the single-stranded DNA translocas...

Full description

Saved in:
Bibliographic Details
Main Authors: Lee, Kyung Suk, Balci, Hamza, Jia, Haifeng, Lohman, Timothy M., Ha, Taekjip
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674262/
https://ncbi.nlm.nih.gov/pubmed/23695672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2882
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items