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Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system

The recognition of cytoplasmic nucleic acid is critical for innate immune responses against microbial infection and is responsible for autoimmunity induced by dead cells. Here, we report the identification of a unique cytosolic nucleic acid cosensor in human airway epithelial cells and fibroblasts:...

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Auteurs principaux: Sugimoto, Naoshi, Mitoma, Hiroki, Kim, Taeil, Hanabuchi, Shino, Liu, Yong-Jun
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040624/
https://ncbi.nlm.nih.gov/pubmed/24821782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400139111
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