RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition

The pronecrotic kinase, receptor interacting protein (RIP1, also called RIPK1) mediates programmed necrosis and, together with its partner, RIP3 (RIPK3), drives midgestational death of caspase 8 (Casp8)-deficient embryos. RIP1 controls a second vital step in mammalian development immediately after b...

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Hlavní autoři: Kaiser, William J., Daley-Bauer, Lisa P., Thapa, Roshan J., Mandal, Pratyusha, Berger, Scott B., Huang, Chunzi, Sundararajan, Aarthi, Guo, Hongyan, Roback, Linda, Speck, Samuel H., Bertin, John, Gough, Peter J., Balachandran, Siddharth, Mocarski, Edward S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040608/
https://ncbi.nlm.nih.gov/pubmed/24821786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401857111
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