RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition

The pronecrotic kinase, receptor interacting protein (RIP1, also called RIPK1) mediates programmed necrosis and, together with its partner, RIP3 (RIPK3), drives midgestational death of caspase 8 (Casp8)-deficient embryos. RIP1 controls a second vital step in mammalian development immediately after b...

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Detalhes bibliográficos
Main Authors: Kaiser, William J., Daley-Bauer, Lisa P., Thapa, Roshan J., Mandal, Pratyusha, Berger, Scott B., Huang, Chunzi, Sundararajan, Aarthi, Guo, Hongyan, Roback, Linda, Speck, Samuel H., Bertin, John, Gough, Peter J., Balachandran, Siddharth, Mocarski, Edward S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040608/
https://ncbi.nlm.nih.gov/pubmed/24821786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401857111
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