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Repair of DNA double-strand breaks by templated nucleotide sequence insertions derived from distant regions of the genome
We used the I-SceI endonuclease to produce DNA double-strand breaks (DSBs) and observed that a fraction of these DSBs were repaired by insertion of sequences, which we termed “templated sequence insertions” (TSIs), derived from distant regions of the genome. These TSIs were derived from genic, retro...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040595/ https://ncbi.nlm.nih.gov/pubmed/24821809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321889111 |
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