Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome

Enterohemorrhagic Escherichia coli (EHEC) is an extracellular pathogen that causes hemorrhagic colitis and hemolytic uremic syndrome. The proinflammatory cytokine, interleukin-1β, has been linked to hemolytic uremic syndrome. Here we identify the nucleotide-binding domain and leucine rich repeat con...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Kailasan Vanaja, Sivapriya, Rathinam, Vijay A. K., Atianand, Maninjay K., Kalantari, Parisa, Skehan, Brian, Fitzgerald, Katherine A., Leong, John M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040571/
https://ncbi.nlm.nih.gov/pubmed/24828532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400075111
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares