PAF and EZH2 Induce Wnt/β-Catenin Signaling Hyperactivation

Fine-control of Wnt signaling is essential for various cellular and developmental decision making processes. However, deregulation of Wnt signaling leads to pathological consequences including cancer. Here, we identify a novel function of PAF, a component of translesion DNA synthesis, in modulating...

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Hauptverfasser: Jung, Hae-Yun, Jun, Sohee, Lee, Moonsup, Kim, Han-Cheon, Wang, Xin, Ji, Hong, McCrea, Pierre D., Park, Jae-Il
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040269/
https://ncbi.nlm.nih.gov/pubmed/24055345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.08.028
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