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Heparan sulfate 3-O-sulfation: A rare modification in search of a function

Many protein ligands bind to heparan sulfate, which results in their presentation, protection, oligomerization or conformational activation. Binding depends on the pattern of sulfation and arrangement of uronic acid epimers along the chains. Sulfation at the C3 position of glucosamine is a relativel...

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Autores principales: Thacker, Bryan E., Xu, Ding, Lawrence, Roger, Esko, Jeffrey D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039620/
https://ncbi.nlm.nih.gov/pubmed/24361527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.12.001
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