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Potentiation of Taxol Efficacy by Discodermolide in Ovarian Carcinoma Xenograft-Bearing Mice

PURPOSE: To evaluate the drug combination of discodermolide and Taxol in human ovarian cancer cells and in an in vivo model of ovarian carcinoma. EXPERIMENTAL DESIGN: The combination index method was used to evaluate the interaction of Taxol and discodermolide in human ovarian SKOV-3 carcinoma cells...

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Main Authors: Huang, Gloria S., Lopez-Barcons, Lluis, Freeze, B. Scott, Smith, Amos B., Goldberg, Gary L., Horwitz, Susan Band, McDaid, Hayley M.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039036/
https://ncbi.nlm.nih.gov/pubmed/16397055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-05-0229
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