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Mechanisms of Taxol resistance related to microtubules

Since its approval by the FDA in 1992 for the treatment of ovarian cancer, the use of Taxol has dramatically increased. Although treatment with Taxol has led to improvement in the duration and quality of life for some cancer patients, the majority eventually develop progressive disease after initial...

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Detalhes bibliográficos
Main Authors: Orr, George A, Verdier-Pinard, Pascal, McDaid, Hayley, Horwitz, Susan Band
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039039/
https://ncbi.nlm.nih.gov/pubmed/14576838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1206934
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