Single and Multiple Dose Pharmacokinetics of Dolutegravir in the Genital Tract of HIV Negative Women

BACKGROUND: Antiretrovirals (ARV) that achieve adequate concentrations in anatomical sites of transmission are of interest for HIV prevention. A Phase 1, open label, pharmacokinetic (PK) study was performed to describe first dose and steady-state PK of the integrase inhibitor dolutegravir (DTG) in b...

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Bibliografiska uppgifter
Huvudupphovsmän: Adams, Jessica L, Patterson, Kristine B, Prince, Heather MA, Sykes, Craig, Greener, Benjamin N, Dumond, Julie B, Kashuba, Angela DM
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038682/
https://ncbi.nlm.nih.gov/pubmed/23899439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2665
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