Bacterial Superantigens Promote Acute Nasopharyngeal Infection by Streptococcus pyogenes in a Human MHC Class II-Dependent Manner

Establishing the genetic determinants of niche adaptation by microbial pathogens to specific hosts is important for the management and control of infectious disease. Streptococcus pyogenes is a globally prominent human-specific bacterial pathogen that secretes superantigens (SAgs) as ‘trademark’ vir...

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Bibliografiska uppgifter
Huvudupphovsmän: Kasper, Katherine J., Zeppa, Joseph J., Wakabayashi, Adrienne T., Xu, Stacey X., Mazzuca, Delfina M., Welch, Ian, Baroja, Miren L., Kotb, Malak, Cairns, Ewa, Cleary, P. Patrick, Haeryfar, S. M. Mansour, McCormick, John K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038607/
https://ncbi.nlm.nih.gov/pubmed/24875883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004155
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